Most conditions. Do you use a standard reticle, or a milling reticle with outer windage and elevation adjustments?
You can use the old wind rosette to help determine your placement, but I prefer to use Todd Hodnett's wind formulae, using BC and MV to determine drift. At that point you can choose to dial in the wind, but most seasoned guys use mil hold-offs that may swell and ebb with changing wind - which is a damn good practice. Most winds are not constant so firm dialing wind can be a crippling habit.
Bring your stuff up one day if you want to try some of this stuff out, it's a lot of fun. We'll punch out to around 500 on average and there's a good place for high angle shooting.