Quote Originally Posted by Dale Gribble View Post
Most loads (caliber/bullet combinations) have a few (handful or less) of powders they work well with, and another handful of powders they work with but are usually not optimal or only work for some loads or have other less than desirable traits.

For rifles I generally try to use one of the powders that work well. For handguns I tend to use something that is less optimal but works across the range of what I shoot. For example, all of my handgun rounds (9, 38spl, 45acp) use unique.

My 223 loads use H335. My 300BO loads are lil gun (supersonic) and soon to be AA1680 (subs, and maybe super too). 7.62x54, 30-06, 30-30 and 8x56R all use IMR 4895.

Also the powder measure and the amount you are producing has an impact. None of my IMR 4895 loads are produced in great numbers, so the fact that its a little difficult to measure with my powder measure isn't an issue, I can hand weigh each charge.

H355, Lil Gun, and Unique all either meter well, or aren't that sensitive in the loads I use that its an issue.
BTW, looking for the ultimate in accuracy usually requires a specific powder and bullet in a specific gun and that is only found via trial and error on your gun.